2,6-Difluoro-4-methoxyphenylboronic Acid (contains varying amounts of Anhydride) - Names and Identifiers
2,6-Difluoro-4-methoxyphenylboronic Acid (contains varying amounts of Anhydride) - Physico-chemical Properties
Molecular Formula | C7H7BF2O3
|
Molar Mass | 187.94 |
Density | 1.35g/cm3 |
Melting Point | 125-130°C(lit.) |
Boling Point | 269.3°C at 760 mmHg |
Flash Point | 116.7°C |
Vapor Presure | 0.00362mmHg at 25°C |
Appearance | White solid |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.485 |
MDL | MFCD05664299 |
Use | Involvement in the Suzuki and Stille coupling reaction for the synthesis of antithrombotic drugs |
2,6-Difluoro-4-methoxyphenylboronic Acid (contains varying amounts of Anhydride) - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
WGK Germany | 3 |
2,6-Difluoro-4-methoxyphenylboronic Acid (contains varying amounts of Anhydride) - Introduction
(2,) boronic acid is an organic compound with the chemical formula C7H7BF2O3. It is a white to pale yellow solid with low solubility.
The compound is mainly used as an important intermediate in organic synthesis. It has similar inhibitory activity to protease and has potential applications in drug research and development. It can also be used as a precursor for the research and synthesis of boronic acid compounds, including supramolecular chemistry, coordination chemistry and the construction of heterocyclic compounds.
(2,) The preparation of boronic acid can usually be obtained from the reaction of para-methoxydibenzene (2,6-difluororo-4-methoxyphenol) and triphenylboron (triphenylborane). Under certain conditions, the two compounds react in an organic solvent to produce the target product.
Regarding safety information,(2,) boronic acid generally has low toxicity when used correctly. However, as an organic synthesis reagent, it should be used in accordance with laboratory safety procedures and follow the relevant safety operating guidelines. Avoid contact with skin and eyes, avoid inhalation or ingestion. During use, good ventilation should be ensured and appropriate protective equipment, such as safety glasses and gloves, should be worn. If you come into contact with this compound, rinse immediately with plenty of water and seek medical help.
Last Update:2024-04-09 20:13:35